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Literature summary for 3.4.22.56 extracted from

  • Cao, X.H.; Liao, Z.Y.; Wang, C.L.; Cai, P.; Yang, W.Y.; Lu, M.F.; Huang, G.W.
    Purification and antitumour activity of a lipopeptide biosurfactant produced by Bacillus natto TK-1 (2009), Biotechnol. Appl. Biochem., 52, 97-106.
    View publication on PubMed
Search for more literature for 3.4.22.56

Activating Compound

Activating Compound Comment Organism Structure
additional information lipopeptide from the producing strain Bacillus natto TK-1, from the traditional Japanese food natto, induces caspase-3 activation Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone a specific caspase 3 inhibitor Homo sapiens
benzyloxycarbonyl-Val-Ala-DL-Asp-fluoromethylketone a general caspase inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens lipopeptide-induced apoptosis in MCF-7 cells is associated with caspase-3 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information lipopeptide-induced apoptosis in MCF-7 cells is associated with caspase-3 Homo sapiens ?
-
 ?
N-acetyl-Asp-Glu-Val-Asp 4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
caspase 3
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens