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Literature summary for 3.4.22.55 extracted from

  • Peintner, L.; Dorstyn, L.; Kumar, S.; Aneichyk, T.; Villunger, A.; Manzl, C.
    The tumor-modulatory effects of caspase-2 and Pidd1 do not require the scaffold protein Raidd (2015), Cell Death Differ., 22, 1803-1811 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus P29594
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General Information

General Information Comment Organism
malfunction loss of caspase-2 leads to an acceleration of tumor onset in the EmΓΌ-Myc mouse lymphoma model Mus musculus
physiological function the enzyme is involved in tumor suppression Mus musculus