Literature summary for 3.4.22.55 extracted from

Sapet, C.; Simoncini, S.; Loriod, B.; Puthier, D.; Sampol, J.; Nguyen, C.; Dignat-George, F.; Anfosso, F.
Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2 (2006), Blood, 108, 1868-1876.

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining
HMEC-1 cell	thrombin initiates EMP generation from the human microvascular endothelial cell line HMEC-1. Caspase-2 plays a role in release of endothelial microparticles by controlling the proteolytic activation of ROCK-II	Homo sapiens	-

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Release 2023.1 (January 2023)