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BRENDA support

Literature summary for 3.4.22.55 extracted from

  • Iwanaga, N.; Kamachi, M.; Aratake, K.; Izumi, Y.; Ida, H.; Tanaka, F.; Tamai, M.; Arima, K.; Nakamura, H.; Origuchi, T.; Kawakami, A.; Eguchi, K.
    Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli (2005), J. Lab. Clin. Med., 145, 105-110.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information etoposide, staurosporine, pacritaxel and cyclohexamide treatment promotes exon 9-inclusion, increasing the ratio of caspase-2S to caspase-2L Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P42575
-
-

Source Tissue

Source Tissue Comment Organism Textmining
U-937 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
caspase-2
-
Homo sapiens
caspase-2L lacks exon 9 after splicing of caspase-2 Homo sapiens
caspase-2S contains exon 9 after splicing of caspase-2 Homo sapiens