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Literature summary for 3.4.22.55 extracted from
- Caspase 2 activity contributes to the initial wave of germ cell apoptosis during the first round of spermatogenesis (2006), Biol. Reprod., 74, 1026-1033.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-CH2F | z-VDVAD-fmk, 0.06 mM in DMSO | Mus musculus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Mus musculus | 5737 | - |
| mitochondrion | - |
Mus musculus | 5739 | - |
| nucleus | - |
Mus musculus | 5634 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 18000 | - |
active form, 1 * 34000 + 1 * 18000, SDS-PAGE | Mus musculus |
| 34000 | - |
active form, 1 * 34000 + 1 * 18000, SDS-PAGE | Mus musculus |
| 48000 | - |
monomer, pro-caspase-2, inactive form, SDS-PAGE | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P29594 | male C57BL/6 | - |
| Mus musculus C57BL/6 | P29594 | male C57BL/6 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| germ cell | - |
Mus musculus | - |
| testis | - |
Mus musculus | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | active form, 1 * 34000 + 1 * 18000, SDS-PAGE | Mus musculus |
| monomer | inactive form, 1 * 48000, SDS-PAGE | Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| caspase-2 | - |
Mus musculus |
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