Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | calmodulin binds the calpain 3 non-catalytic domain C2L and promotes enzyme activation | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
C129S | inactive | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
94000 | - |
x * 94000, full-length enzyme, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q64691 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
titin + H2O | - |
Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 94000, full-length enzyme, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
calpain 3 | - |
Mus musculus |
CAPN3 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | mutations of calpain 3 cause limb-girdle dystrophy 2A | Mus musculus |