Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | NF-kappaB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle fibre | isolated from LGMD2A patients. CAPN3 intervenes in the regulation of the expression of NF-kappaB-dependent survival genes to prevent apoptosis in skeletal muscle. Deregulations in the NF-kappaB pathway could be part of the mechanism responsible for the muscle wasting resulting from CAPN3 deficiency | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | NF-kappaB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CAPN3 | - |
Homo sapiens |