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Literature summary for 3.4.22.53 extracted from

  • Lin, I.J.; Zhou, Z.; Crusselle-Davis, V.J.; Moghimi, B.; Gandhi, K.; Anantharaman, A.; Pantic, D.; Huang, S.; Jayandharan, G.; Zhong, L.; Srivastava, A.; Bungert, J.
    Calpeptin increases the activity of upstream stimulatory factor and induces high level globin gene expression in erythroid cells (2009), J. Biol. Chem., 284, 20130-20135.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
calpeptin
-
Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythroleukemia cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
upstream stimulatory factor + H2O
-
Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
m-calpain
-
Mus musculus

General Information

General Information Comment Organism
malfunction inhibition of m-calpain induces expression of the adult alpha- and beta-globin genes Mus musculus