Literature summary for 3.4.22.53 extracted from

Liu, S.H.; Yang, C.N.; Pan, H.C.; Sung, Y.J.; Liao, K.K.; Chen, W.B.; Lin, W.Z.; Sheu, M.L.
IL-13 downregulates PPAR-gamma/heme oxygenase-1 via ER stress-stimulated calpain activation: aggravation of activated microglia death (2010), Cell. Mol. Life Sci., 67, 1465-1476.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
microglia	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
calpain II	-	Rattus norvegicus

Expression

Organism	Comment	Expression
Rattus norvegicus	endoplasmic reticulum stress stimulates calpain II activation, interleukin-13 enhances endoplasmic reticulum stress-regulated calpain activation and calpain-II expression in lipopolysaccaride-activated microglia	up

General Information

General Information	Comment	Organism
physiological function	an endoplasmic reticulum stress-related calpain-down-regulated PPAR-gamma/HO-1 pathway is involved in the interleukin-13-enhanced activated death of microglia	Rattus norvegicus

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Release 2023.1 (January 2023)