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Literature summary for 3.4.22.53 extracted from

  • Hata, S.; Koyama, S.; Kawahara, H.; Doi, N.; Maeda, T.; Toyama-Sorimachi, N.; Abe, K.; Suzuki, K.; Sorimachi, H.
    Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP (2006), J. Biol. Chem., 281, 11214-11224.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus functions for nCL-2 involve the membrane trafficking of mucus cells by interacting with coat proteins ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
duodenal mucosa nCL-2 is localized strictly to the surface cells in the gastric epithelium and the mucus-secreting goblet cells in the duodenum Mus musculus
-
goblet cell nCL-2 is localized strictly to the surface cells in the gastric epithelium and the mucus-secreting goblet cells in the duodenum Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-subunit of coatomer complex beta-COP + H2O
-
Mus musculus ?
-
?
additional information functions for nCL-2 involve the membrane trafficking of mucus cells by interacting with coat proteins Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
nCL-2
-
Mus musculus