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BRENDA support

Literature summary for 3.4.22.52 extracted from

  • Rudic, B.; Song, H.; Breedijk, A.; Brinkkoetter, P.; Beck, G.; Yard, B.; Ponelies, N.
    Hypothermic preservation up-regulates calpain expression and increases ubiquitination in cultured vascular endothelial cells: influence of dopamine pretreatment (2010), J. Surg. Res., 160, 325-332.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
calpain 1
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Homo sapiens
mu-calpain
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens cold storage (at 4°C) induces a time dependent up-regulation of calpain 1, reflected by an increase in the autoproteolytic cleavage of calpain 1, which can be prevented by addition of EDTA or dopamine (0.025 mM) pretreatment up

General Information

General Information Comment Organism
malfunction calpain inhibition does not protect endothelial cells during cold storage Homo sapiens