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Literature summary for 3.4.22.52 extracted from

  • Liu, T.; Schneider, R.A.; Shah, V.; Huang, Y.; Likhotvorik, R.I.; Keshvara, L.; Hoyt, D.G.
    Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells (2009), J. Inflamm., 6, 20.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
carbobenzoxy-valinyl-phenylalaninal
-
 Sus scrofa
MDL-28170
-
 Sus scrofa
PD150606
-
 Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
COX-2 + H2O
-
 Sus scrofa ?
-
 ?
[4-((4-(dimethylamino)phenyl)azo)benzoic acid, succinimidyl ester]-Thr-Pro-Leu-Lys-Ser-Pro-Pro-Pro-Ser-Pro-Arg-[5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid] + H2O
-
 Sus scrofa ?
-
 ?

Synonyms

Synonyms Comment Organism
mu-calpain
-
 Sus scrofa

Expression

Organism Comment Expression
Sus scrofa Protein Never in Mitosis Gene A Interacting-1 reduces calpain activity and slows the degradation of COX-2 in MAEC cells down