Literature summary for 3.4.22.52 extracted from

Berg, U.; Bang, P.; Carlsson-Skwirut, C.
Calpain proteolysis of insulin-like growth factor binding protein (IGFBP) -2 and -3, but not of IGFBP-1 (2007), Biol. Chem., 388, 859-863.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
insulin-like growth factor binding protein-2 + H2O	the primary cleavage site in insulin-like growth factor binding protein-2 is localized to the non-conserved central linker regions	Homo sapiens	?	-	?
insulin-like growth factor binding protein-3 + H2O	the primary cleavage site in insulin-like growth factor binding protein-3 is localized to the non-conserved central linker regions. In vitro binding of mu-calpain to insulin-like growth factor binding protein-3 is a Ca2+-dependent reaction with a rapid on/off rate	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)