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Literature summary for 3.4.22.51 extracted from

  • Duschak, V.G.; Barboza, M.; Couto, A.S.
    Trypanosoma cruzi: partial characterization of minor cruzipain isoforms non-adsorbed to concanavalin A-Sepharose (2003), Exp. Parasitol., 104, 122-130.
    View publication on PubMed
Search for more literature for 3.4.22.51

Inhibitors

Inhibitors Comment Organism Structure
E-64
-
 Trypanosoma cruzi

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
12000
-
 x * 12000, non-adsorbed (to concanavalin A-Sepharose) cruzipain isoform, SDS-PAGE Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
a subset of cruzipain molecules Trypanosoma cruzi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-Phe-Val-Arg-p-nitroanilide + H2O as active as with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
benzoyl-Pro-Phe-Arg-p-nitroanilide + H2O 41% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
benzoyl-Val-Gly-Arg-p-nitroanilide + H2O 52% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
benzyloxycarbonyl-Ala-Arg-Arg-methoxy-beta-naphthylamide + H2O 36% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide + H2O
-
 Trypanosoma cruzi ?
-
 ?
benzyloxycarbonyl-Gly-Pro-Arg-p-nitroanilide + H2O 66% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
benzyloxycarbonyl-Phe-Arg-methoxy-beta-naphthylamide + H2O 30% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
N-tert-butoxycarbonyl-O-benzyl-Ser-Gly-Arg-p-nitroanilide + H2O 39% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
N-tert-butoxycarbonyl-Val-Leu-Gly-Arg-p-nitroanilide + H2O 24% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi ?
-
 ?
tosyl-Gly-Pro-Arg-p-nitroanilide + H2O 25% of the activity with benzyloxycarbonyl-Arg-Arg-methoxy-beta-naphthylamide Trypanosoma cruzi tosyl-Gly-Pro-Arg + p-nitroaniline
-
 ?

Subunits

Subunits Comment Organism
? x * 12000, non-adsorbed (to concanavalin A-Sepharose) cruzipain isoform, SDS-PAGE Trypanosoma cruzi

Synonyms

Synonyms Comment Organism
cruzipain
-
 Trypanosoma cruzi
NACrI non-adsorbed (to concanavalin A-Sepharose) cruzipain isoform Trypanosoma cruzi