Inhibitors | Comment | Organism | Structure |
---|---|---|---|
E-64 | - |
Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CXCR2 + H2O | Staphylococcus aureus | the enzyme specifically cleaves the N-terminal domain of human CXCR2 between asparate-35 and alanine-36 | ? | - |
? | |
CXCR2 + H2O | Staphylococcus aureus MRSA | the enzyme specifically cleaves the N-terminal domain of human CXCR2 between asparate-35 and alanine-36 | ? | - |
? | |
additional information | Staphylococcus aureus | staphopain A does not cleave human CXCR1 | ? | - |
? | |
additional information | Staphylococcus aureus MRSA | staphopain A does not cleave human CXCR1 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Staphylococcus aureus MRSA | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CXCR2 + H2O | the enzyme specifically cleaves the N-terminal domain of human CXCR2 between asparate-35 and alanine-36 | Staphylococcus aureus | ? | - |
? | |
CXCR2 + H2O | the enzyme specifically cleaves the N-terminal domain of human CXCR2 between asparate-35 and alanine-36 | Staphylococcus aureus MRSA | ? | - |
? | |
additional information | staphopain A does not cleave human CXCR1 | Staphylococcus aureus | ? | - |
? | |
additional information | staphopain A does not cleave human CXCR1 | Staphylococcus aureus MRSA | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
staphylopain | - |
Staphylococcus aureus |
General Information | Comment | Organism |
---|---|---|
physiological function | staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis | Staphylococcus aureus |