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Literature summary for 3.4.22.47 extracted from
- Cleavage of protease-activated receptors on an immortalized oral epithelial cell line by Porphyromonas gingivalis gingipains (2009), Microbiology, 155, 3238-3246.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protease-activated receptor-2 + H2O | Porphyromonas gingivalis | specific substrate for Lys-gingipain | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protease-activated receptor-2 + H2O | specific substrate for Lys-gingipain | Porphyromonas gingivalis | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KGP | - |
Porphyromonas gingivalis |
| Lys-gingipain | - |
Porphyromonas gingivalis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | human keratinocyte Rgp-deficient and Kgp-deficient double mutant cells do not cleave protease-activated recptor-1 and -2. The single Kgp-negative mutant cleaves protease-activated recptor-1 | Porphyromonas gingivalis |
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