Cloned (Comment) | Organism |
---|---|
HbR domain is recombinantly expressed in Escherichia coli | Porphyromonas gingivalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
gingipain | - |
Porphyromonas gingivalis |
HbR | adhesin domain of gingipain which is able to bind heme as an iron nutrient source for Porphyromonas gingivalis | Porphyromonas gingivalis |
General Information | Comment | Organism |
---|---|---|
physiological function | using erythrocyte and its membrane as a model, it is shown that recombinant HbR expressed in Escherichia coli can inhibit heme-induced haemolysis, probably through removing heme from the heme-membrane complex and lowering free heme toxicity by mediating dimerization of heme molecules | Porphyromonas gingivalis |