Any feedback?
Literature summary for 3.4.22.47 extracted from
- Roles of Arg- and Lys-gingipains in coaggregation of Porphyromonas gingivalis: identification of its responsible molecules in translation products of rgpA, kgp, and hagA genes (2004), Biol. Chem., 385, 1041-1047.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| KYT-36 | specific inhibition of Kgp, slightly inhibits coaggregation of Porphyromonas gingivalis with other bacteria in vivo | Porphyromonas gingivalis |  |
| lysine | slight inhibition of coaggregation of Porphyromonas gingivalis with other oral bacteria by L-lysine and more slightly by D-lysine | Porphyromonas gingivalis | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Porphyromonas gingivalis | gingipain K adds to gingipain R-mediated coaggregation of Porphyromonas gingivalis with other oral bacteria, it is a virulence factor, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
strain ATCC 33277, gene kgp | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | gingipain K adds to gingipain R-mediated coaggregation of Porphyromonas gingivalis with other oral bacteria, it is a virulence factor, overview | Porphyromonas gingivalis | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KGP | - |
Porphyromonas gingivalis |
| Lys-gingipain | - |
Porphyromonas gingivalis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
coaggregation assay at room temperature | Porphyromonas gingivalis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
coaggregation assay at | Porphyromonas gingivalis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
