Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic translation initiation factor eIF4GI + H2O | Foot-and-mouth disease virus | eukaryotic host cell protein substrate, cleavage causes the rapid inhibition of cellular cap-dependent protien synthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Foot-and-mouth disease virus | - |
FMDV O1Kaufbeuren B64, from BHK or A293 cells, two enzymes: leader protease and 3C protease | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic translation initiation factor eIF4GI + H2O | eukaryotic host cell protein substrate, cleavage causes the rapid inhibition of cellular cap-dependent protien synthesis | Foot-and-mouth disease virus | ? | - |
? | |
eukaryotic translation initiation factor eIF4GI + H2O | eukaryotic host cell protein substrate, activity of 3Cpro and Lpro with wild-type and mutant substrate, overview, the highly specific 3Cpro cleavage site is located at the small 40-amino-acid region of the protein | Foot-and-mouth disease virus | ? | - |
? | |
additional information | elIF4GI cleavage site mapping | Foot-and-mouth disease virus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3C protease | - |
Foot-and-mouth disease virus |
3Cpro | - |
Foot-and-mouth disease virus |
leader protease | - |
Foot-and-mouth disease virus |
Lpro | - |
Foot-and-mouth disease virus |