Literature summary for 3.4.22.45 extracted from

Ivanov, K.I.; Eskelin, K.; Basic, M.; De, S.; Lohmus, A.; Varjosalo, M.; Maekinen, K.
Molecular insights into the function of the viral RNA silencing suppressor HCPro (2016), Plant J., 85, 30-45 .

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Organism

Organism	UniProt	Comment	Textmining
potato virus A	-	-	-

Synonyms

Synonyms	Comment	Organism
HcPro	-	potato virus A

General Information

General Information	Comment	Organism
metabolism	potyviral helper component proteinase is a suppressor of antiviral RNA silencing. HCPro and ARGONAUTE1 (AGO1), the core component of the RNA-induced silencing complex (RISC), interact with each other and are both associated with ribosomes in planta. A mechanism is suggested in which Potyviral helper component proteinase complexes containing viral and host proteins act to suppress antiviral RNA silencing through local disruption of the methionine cycle	potato virus A

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Release 2023.1 (January 2023)