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Literature summary for 3.4.22.44 extracted from
- Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimers disease mitigates Abeta pathology and improves cognitive function (2012), Exp. Mol. Med., 44, 740-748.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293T cells and Mus musculus brain | turnip mosaic virus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| amyloid-beta + H2O | turnip mosaic virus | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| turnip mosaic virus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| amyloid-beta + H2O | - |
turnip mosaic virus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| protease NIa | - |
turnip mosaic virus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | protease NIa not only reduces amyloid-beta pathology, but also improves behavioral deficits in mice | turnip mosaic virus |
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