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Literature summary for 3.4.22.43 extracted from

  • Huang, K.; Gao, L.; Yang, M.; Wang, J.; Wang, Z.; Wang, L.; Wang, G.; Li, H.
    Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin II-induced hypertrophy (2017), Int. J. Biochem. Cell Biol., 89, 6-15 .
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information CTSV knockdown by RNAi Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O60911
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiomyocyte
-
Homo sapiens
-
HCM cell
-
Homo sapiens
-
heart
-
Homo sapiens
-
myocardium
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
CTSV
-
Homo sapiens

General Information

General Information Comment Organism
physiological function exogenous cathepsin V protein protects human cardiomyocytes from angiotensin II-induced hypertrophy, human cardiomyocytes hypertrophic cardiomyopathy (HCM) as a cell model to investigate the effects of exogenous CTSV on Ang II-induced cardiac cell hypertrophy, overview. Analysis of the mechanism of CTSV cardioprotection, overview. Exogenous CTSV inhibits Ang II-induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR Homo sapiens