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Literature summary for 3.4.22.41 extracted from

  • Kang, J.M.; Ju, H.L.; Sohn, W.M.; Na, B.K.
    Defining the regulatory and inhibitory elements within the prodomain of CsCF-6, a cathepsin F cysteine protease of Clonorchis sinensis (2013), Mol. Biochem. Parasitol., 190, 92-96.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli M15 [pREP4] cells Clonorchis sinensis

Inhibitors

Inhibitors Comment Organism Structure
additional information the prodomain effectively inhibits the enzyme in which the ERFNAQ motif plays a critical role in the inhibition, but the GTFD motif is also required for complete inhibition Clonorchis sinensis

Organism

Organism UniProt Comment Textmining
Clonorchis sinensis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Clonorchis sinensis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-L-leucyl-L-arginyl-7-amido-4-methylcoumarin + H2O
-
Clonorchis sinensis benzyloxycarbonyl-L-leucyl-L-arginine + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
CF-6
-
Clonorchis sinensis