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Literature summary for 3.4.22.40 extracted from
- Quantification of neutral cysteine protease bleomycin hydrolase and its localization in rat tissues (2007), J. Biochem., 141, 69-76.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | hepatocytes | Rattus norvegicus | 5829 | - |
| rough endoplasmic reticulum | outer membrane of, kidney epithel | Rattus norvegicus | 5791 | - |
| rough endoplasmic reticulum | outer membrane of, liver hepatocytes | Rattus norvegicus | 5791 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | P70645 | encoded by Blmh gene; Wistar rats | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| gel filtration, SDS-PAGE | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | 6-week-old rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| erythrocyte | extracts, bleomycin hydrolase detection by Western blot | Rattus norvegicus | - |
| hepatocyte | detected by immunohistochemistry | Rattus norvegicus | - |
| kidney | of 6-week-old rats, tissue amounts of bleomycin hydrolase determined, relative high amounts detected | Rattus norvegicus | - |
| leukocyte | leukocyte-rich cell extracts, detection by Western blot | Rattus norvegicus | - |
| liver | of 6-week-old rats, tissue amounts of bleomycin hydrolase determined, relative high amounts detected | Rattus norvegicus | - |
| lung | of 6-week-old rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| neuron | bleomycin hydrolase detected by immunohistochemistry | Rattus norvegicus | - |
| ovary | 6-week-old female rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| pancreas | of 6-week-old rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| RBL-2H3 cell | hemo-lymphocytic lineage cell line, bleomycin hydrolase detection by Western blot | Rattus norvegicus | - |
| skeletal muscle | of 6-week-old rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| skin | newborn rats, tissue amounts of bleomycin hydrolase determined, high amounts detected | Rattus norvegicus | - |
| spleen | of 6-week-old rats, red pulpy region, detected by immunohistochemistry | Rattus norvegicus | - |
| stomach | of 6-week-old rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| testis | 6-week-old male rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
| uterus | 6-week-old female rats, tissue amounts of bleomycin hydrolase determined | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
detection of bleomycin hydrolase by ELISA, Western blot, immunohistochemistry and immunoelectron microscopic, present in the range between 3.7 and 131.1 ng per mg of rat tissues | Rattus norvegicus |
| additional information | - |
detection of bleomycin hydrolase by ELISA, Western blot, immunohistochemistry and immunoelectron microscopic, present in the range between 3.7 and 131.1 ng per mg of rat tissues, increased at 6 weeks after birth, then slightly decreased | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BH protein | - |
Rattus norvegicus |
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