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Literature summary for 3.4.22.39 extracted from

  • Webster, A.; Leith, I.R.; Hay, R.T.
    The protease of adenovirus serotype 2 requires cysteine residues for both activation and catalysis (1994), J. Virol., 68, 7292-7300.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
DTT activation unidentified adenovirus
GVQSLKRRRCF required unidentified adenovirus
GVQSLKRRRCF pVI-CT, disulfide-linked unidentified adenovirus
viral DNA not required in vitro unidentified adenovirus

Cloned(Commentary)

Cloned (Comment) Organism
expression in Sf9/baculovirus cells unidentified adenovirus

Organism

Organism UniProt Comment Textmining
unidentified adenovirus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-/-Xaa- and -Yaa-Xaa-Gly-Xaa-/-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid) consensus sequences unidentified adenovirus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Leu-Ser-Gly-Gly-Ala-Phe-Ser-Trp
-
unidentified adenovirus Leu-Ser-Gly-Gly + Ala-Phe-Ser-Trp
-
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