Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
matrix-metalloproteinase-9 + H2O | Homo sapiens | cathepsin K is responsible for the activation of pro-MMP-9. Knocking down cathepsin K in MDA-MB-231 cells also diminishes MMP-9 activity compared to wild type control | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P43235 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MDA-MB-231 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
matrix-metalloproteinase-9 + H2O | - |
Homo sapiens | ? | - |
? | |
matrix-metalloproteinase-9 + H2O | cathepsin K is responsible for the activation of pro-MMP-9. Knocking down cathepsin K in MDA-MB-231 cells also diminishes MMP-9 activity compared to wild type control | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CTSK | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | cathepsin K can cleave and activate MMP-9 in acidic environments such as seen in tumors and during bone resorption | Homo sapiens |