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Literature summary for 3.4.22.37 extracted from
- Gingipains produced by Porphyromonas gingivalis ATCC49417 degrade human-beta-defensin 3 and affect peptides antibacterial activity in vitro (2011), Peptides, 32, 1073-1077.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| leupeptin | - |
Porphyromonas gingivalis |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| human beta-defensin 3 + H2O | - |
Porphyromonas gingivalis | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gingipain R | - |
Porphyromonas gingivalis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Porphyromonas gingivalis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | results suggest that gingipains may have a role in the resistance of Porphyromonas gingivalis ATCC 49417 to human beta-defensin 3 | Porphyromonas gingivalis |
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