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Literature summary for 3.4.22.37 extracted from
- Inhibition of Porphyromonas gingivalis proteinases (gingipains) by chlorhexidine: synergistic effect of Zn(II) (2006), Oral Microbiol. Immunol., 21, 212-217.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Chlorhexidine | synergistic effect of Zn2+ in a 1:1 ratio of chlorhexidine and Zn2+ | Porphyromonas gingivalis |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | enhances the inhibitory effect of chlorhexidine | Porphyromonas gingivalis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzoyl-Arg-4-nitroanilide + H2O | - |
Porphyromonas gingivalis | benzoyl-Arg + 4-nitroaniline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Arg-gingipain | - |
Porphyromonas gingivalis |
| HRgpA | - |
Porphyromonas gingivalis |
| RgpB | - |
Porphyromonas gingivalis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
assay at room temperature | Porphyromonas gingivalis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.6 | - |
assay at | Porphyromonas gingivalis |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | inhibition kinetics | Porphyromonas gingivalis |
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