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Literature summary for 3.4.22.36 extracted from

  • Brough, D.; Pelegrin, P.; Rothwell, N.J.
    Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc (2009), Eur. J. Immunol., 39, 352-358.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.36

Activating Compound

Activating Compound Comment Organism Structure
additional information pannexin-1-dependent caspase-1 activation is regulated by zinc and induced by ATP, molecular mechanism Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular the enzyme is secreted by macrophages Mus musculus
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Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ pannexin-1-dependent caspase-1 activation is regulated by zinc and induced by ATP, molecular mechanism Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus enzyme regulation, mechanisms of ATP-induced and caspase-1-dependent cell death and interleukin-1beta release are both regulated by zinc, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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 adult, male C57BL/6 mice
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Source Tissue

Source Tissue Comment Organism Textmining
macrophage
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 Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme regulation, mechanisms of ATP-induced and caspase-1-dependent cell death and interleukin-1beta release are both regulated by zinc, overview Mus musculus ?
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 ?