Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iodoacetamide | - |
Sus scrofa | |
additional information | no inhibition by E-64 and EDTA | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome | - |
Sus scrofa | 5768 | - |
lysosome | - |
Sus scrofa | 5764 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein + H2O | Sus scrofa | enzyme is critically involved in the lysosomal processing of bacterial antigens for MHC class II presentation | peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
purified enzyme | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-lymphocyte cell line | WT51 cell, EBV-transformed | Sus scrofa | - |
culture condition:antigen-presenting cell | different types | Sus scrofa | - |
dendritic cell | resting and maturing | Sus scrofa | - |
kidney | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Ala-Glu-Asn-Xaa-Ala-Glu-Lys-NH2 + H2O | substrate specificity at S1 position, overview | Sus scrofa | benzyloxycarbonyl-Ala-Glu-Asn + Xaa-Ala-Glu-Lys-NH2 | - |
? | |
benzyloxycarbonyl-Val-Ala-Asn-4-methylcoumarin-7-amide + H2O | fluorogenic substrate | Sus scrofa | benzyloxycarbonyl-Val-Ala-Asn + 7-amino-4-methylcoumarin | - |
? | |
myelin basic protein MBP + H2O | cleavage sites at positions 84-85 and 92-93, multiple-sclerosis-associated autoantigen, digestion, destruction of the immunodominant epitope 83-99 | Sus scrofa | 5 fragments | product determination | ? | |
protein + H2O | enzyme is critically involved in the lysosomal processing of bacterial antigens for MHC class II presentation | Sus scrofa | peptides | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AEP | - |
Sus scrofa |
Asparaginyl endopeptidase | - |
Sus scrofa |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.8 | - |
assay at | Sus scrofa |