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Literature summary for 3.4.22.29 extracted from

  • Sun, Y.; Wang, X.; Yuan, S.; Dang, M.; Li, X.; Zhang, X.C.; Rao, Z.
    An open conformation determined by a structural switch for 2A protease from coxsackievirus A16 (2013), Protein Cell, 4, 782-792.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.29

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Coxsackievirus A16

Inhibitors

Inhibitors Comment Organism Structure
EDTA the enzyme is slightly inhibited by 10 mM EDTA Coxsackievirus A16

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ contains zinc Coxsackievirus A16

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
eukaryotic translation initiation factor 4G I + H2O Coxsackievirus A16
-
 ?
-
 ?
eukaryotic translation initiation factor 4G II + H2O Coxsackievirus A16
-
 ?
-
 ?
thrombin + H2O Coxsackievirus A16
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Coxsackievirus A16 Q9QF31
-
-

Purification (Commentary)

Purification (Comment) Organism
HiTrap Q column chromatography Coxsackievirus A16

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
eukaryotic translation initiation factor 4G I + H2O
-
 Coxsackievirus A16 ?
-
 ?
eukaryotic translation initiation factor 4G II + H2O
-
 Coxsackievirus A16 ?
-
 ?
thrombin + H2O
-
 Coxsackievirus A16 ?
-
 ?

Subunits

Subunits Comment Organism
hexamer x-ray crystallography Coxsackievirus A16

Synonyms

Synonyms Comment Organism
2A protease
-
 Coxsackievirus A16
2Apro
-
 Coxsackievirus A16