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Literature summary for 3.4.22.27 extracted from

  • Minematsu, N.; Nakamura, H.; Furuuchi, M.; Nakajima, T.; Takahashi, S.; Tsujimura, S.; Tateno, H.; Ishizaka, A.
    Common functional polymorphisms in the cathepsin S promoter in Japanese subjects: possible contribution to pulmonary emphysema (2008), Respirology, 13, 498-504.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens cathepsin S is putatively involved in the pathogenesis of COPD ?
-
 ?
additional information Homo sapiens this enzyme serves a crucial role in MHC class II mediated immune systems, resulting in CD4+ T cell activation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P25774 reference no. rs7534124, A/G type single strand conformation polymorphism
-

Source Tissue

Source Tissue Comment Organism Textmining
blood from COPD patients Homo sapiens
-
dendritic cell
-
 Homo sapiens
-
macrophage
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cathepsin S is putatively involved in the pathogenesis of COPD Homo sapiens ?
-
 ?
additional information this enzyme serves a crucial role in MHC class II mediated immune systems, resulting in CD4+ T cell activation Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
cathepsin S
-
 Homo sapiens
CTSS
-
 Homo sapiens
rs1136774 A/G type single strand conformation polymorphism Homo sapiens
rs16827671 A/G type single strand conformation polymorphism Homo sapiens
rs34495036 (TCCC)ins/del type single strand conformation polymorphism Homo sapiens
rs35989725 (CA)11/12 (VNTR) type single strand conformation polymorphism Homo sapiens
rs3754212 T/C type single strand conformation polymorphism Homo sapiens
rs7534124 A/G type single strand conformation polymorphism Homo sapiens