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Literature summary for 3.4.22.27 extracted from

  • Boes, M.; van der Wel, N.; Peperzak, V.; Kim, Y.M.; Peters, P.J.; Ploegh, H.
    In vivo control of endosomal architecture by class II-associated invariant chain and cathepsin S (2005), Eur. J. Immunol., 35, 2552-2562.
    View publication on PubMed
Search for more literature for 3.4.22.27

Protein Variants

Protein Variants Comment Organism
additional information generation of enzyme-deficient mutant murine splenocytes, which show enlarged endosome forms lacking the multivesicular morphology due to accumulation of MHC class II-associated invariant chain Ii, cells lacking both CatS and MHC class II-associated invariant chain Ii show normal endosome size but absence of endosomal membranes Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome
-
 Mus musculus 5768
-
lysosome
-
 Mus musculus 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
MHC class II-associated invariant chain Ii + H2O Mus musculus degradation, cathepsin S and MHC class II-associated invariant chain Ii are responsible for in vivo control of endosomal size and multivesicular morphology ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
B-cell primary Mus musculus
-
splenocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
MHC class II-associated invariant chain Ii + H2O degradation Mus musculus ?
-
 ?
MHC class II-associated invariant chain Ii + H2O degradation, cathepsin S and MHC class II-associated invariant chain Ii are responsible for in vivo control of endosomal size and multivesicular morphology Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
CatS
-
 Mus musculus