Application | Comment | Organism |
---|---|---|
pharmacology | the enzyme might be a good target for development of inhibitors in treatment of collagen-induced arthritis and autoimmune myasthenia gravis | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | cathepsin S-deficient mutant mice show impaired degradation of the invariant chain in antigen presenting cells alng with resistance to collagen-induced arthritis and autoimmune myasthenia gravis | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | diverse arylaminoethyl amides as noncovalent inhibitors of cathepsin S with IC50 in the nanomolar range, optimization of P1 and N-aryl, binding specificities of positions P1 and P2, and of subsite S1, overview | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |