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Literature summary for 3.4.22.2 extracted from
- Proteases, actinidin, papain and trypsin reduce oral biofilm on the tongue in elderly subjects and in vitro (2017), Arch. Oral Biol., 82, 233-240 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | dental plaque is a causative factor for oral disease and a potential reservoir for respiratory infection in the elderly. Therefore, there is a critical need for the development of effective methods to remove oral biofilm. Proteases reduce oral biofilm in vivo in elderly subjects. Tablets containing actinidin remove tongue coating in elderly subjects. Oral Actinomyces biofilm is significantly reduced by the proteases papain, actinidin and trypsin. Papain and trypsin effectively digest the major fimbrial proteins, FimP and FimA, from Actinomyces. Actinidin, papain and trypsin reduce multispecies biofilm that is reconstructed in vitro. Papain and trypsin inhibit formation of multispecies biofilm in vitro | Carica papaya |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carica papaya | P00784 | - |
- |
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