Application | Comment | Organism |
---|---|---|
medicine | treatment with cathepsin L inhibitors significantly reduces the replication of caliciviruses | feline calicivirus |
medicine | treatment with cathepsin L inhibitors significantly reduces the replication of caliciviruses | Murine norovirus 1 |
medicine | treatment with cathepsin L inhibitors significantly reduces the replication of caliciviruses | Porcine enteric sapovirus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Phe-Tyr-CHO | - |
feline calicivirus | |
benzyloxycarbonyl-Phe-Tyr-CHO | - |
Murine norovirus 1 | |
benzyloxycarbonyl-Phe-Tyr-CHO | - |
Porcine enteric sapovirus | |
MDL28170 | - |
feline calicivirus | |
MDL28170 | - |
Murine norovirus 1 | |
MDL28170 | - |
Porcine enteric sapovirus | |
additional information | not inhibited by CA074Me | feline calicivirus | |
additional information | not inhibited by CA074Me | Murine norovirus 1 | |
additional information | not inhibited by CA074Me | Porcine enteric sapovirus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
feline calicivirus | - |
- |
- |
Murine norovirus 1 | - |
- |
- |
Porcine enteric sapovirus | - |
- |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin L activity is required for calicivirus replication | feline calicivirus |
physiological function | cathepsin L activity is required for calicivirus replication | Murine norovirus 1 |
physiological function | cathepsin L activity is required for calicivirus replication | Porcine enteric sapovirus |