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Literature summary for 3.4.22.15 extracted from

  • Sansri, V.; Meemon, K.; Changklungmoa, N.; Kueakhai, P.; Chantree, P.; Chaichanasak, P.; Lorsuwannarat, N.; Itagaki, T.; Sobhon, P.
    Protection against Fasciola gigantica infection in mice by vaccination with recombinant juvenile-specific cathepsin L (2015), Vaccine, 33, 1596-1601.
    View publication on PubMed
Search for more literature for 3.4.22.15

Application

Application Comment Organism
medicine subcutaneous injections of recombinant pro-enzyme of Fasciola gigantica in mice elicit high levels of protection against challenge infections with the Fasciola gigantica metacercariae Fasciola gigantica

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris Fasciola gigantica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 x * 45000, SDS-PAGE Fasciola gigantica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Fasciola gigantica
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Fasciola gigantica Q6T857
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni2+-NTA column chromatography, and gel filtration Fasciola gigantica

Source Tissue

Source Tissue Comment Organism Textmining
juvenile
-
 Fasciola gigantica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Fasciola gigantica benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?
Gelatin + H2O
-
 Fasciola gigantica ?
-
 ?

Subunits

Subunits Comment Organism
? x * 45000, SDS-PAGE Fasciola gigantica

Synonyms

Synonyms Comment Organism
cathepsin L1H
-
 Fasciola gigantica
CatL1H
-
 Fasciola gigantica