Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.15 extracted from

  • Urbich, C.; Heeschen, C.; Aicher, A.; Sasaki, K.; Bruhl, T.; Farhadi, MR.; Vajkoczy, P.; Hofmann, W.K.; Peters, C.; Pennacchio, L.A.; Abolmaali, N.D.; Chavakis, E.; Reinheckel, T.; Zeiher, A.M.; Dimmeler, S.
    Cathepsin L is required for endothelial progenitor cell-induced neovascularization (2005), Nat. Med., 11, 206-213.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
novascularization is significantly impaired in cathepsin L-deficient mice
-

Source Tissue

Source Tissue Comment Organism Textmining
blood vessel endothelium cathepsin L is highly expressed in endothelial progenitor cells compared to mature endothelial cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O
-
Mus musculus benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
?
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O
-
Homo sapiens benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
?
Gelatin + H2O
-
Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
Cath L
-
Mus musculus
Cath L
-
Homo sapiens
cathepsin L
-
Mus musculus
cathepsin L
-
Homo sapiens