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Literature summary for 3.4.22.15 extracted from

  • Al-Jassabi, S.
    Purification and characterization of cathepsin L from skeletal muscle of the lizard Agama stellio stellio (2000), Biochemistry (Moscow), 65, 959-962.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
thiol-reducing reagent required for activation Agama stellio stellio

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme is inhibited by cysteine proteases inhibitors Agama stellio stellio

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0014
-
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
Agama stellio stellio

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34000
-
-
Agama stellio stellio

Organism

Organism UniProt Comment Textmining
Agama stellio stellio
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Agama stellio stellio

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
Agama stellio stellio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
Agama stellio stellio ?
-
?
Hemoglobin + H2O
-
Agama stellio stellio ?
-
?
Insulin B-chain + H2O
-
Agama stellio stellio ?
-
?
serum albumin + H2O
-
Agama stellio stellio ?
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
6.2
-
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
Agama stellio stellio

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.1
-
-
Agama stellio stellio

pI Value

Organism Comment pI Value Maximum pI Value
Agama stellio stellio
-
-
5.5