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Literature summary for 3.4.21.B7 extracted from

  • Gal, P.; Dobo, J.; Zavodszky, P.; Sim, R.B.
    Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions (2009), Mol. Immunol., 46, 2745-2752.
    View publication on PubMed
Search for more literature for 3.4.21.B7

Organism

Organism UniProt Comment Textmining
Homo sapiens P48740
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
antithrombin + H2O cleavage at R425-/-S425 Homo sapiens ?
-
 ?
C1-inhibitor + H2O cleavage at R466-/-T467 Homo sapiens ?
-
 ?
complement component C2 + H2O cleavage at R243-/-K244 Homo sapiens ?
-
 ?
factor XIII + H2O cleavage at R38-/-G39 Homo sapiens ?
-
 ?
fibrinogen beta-chain + H2O cleavage at R44-/-G45 and other sites Homo sapiens ?
-
 ?
additional information autoactivation by cleavage of R448-/-I449. The enzyme is relatively unspecific Homo sapiens ?
-
 ?
protease activated receptor 4 + H2O cleavage at R47-/-G48 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
MASP-1
-
 Homo sapiens