Literature summary for 3.4.21.B6 extracted from

Ma, X.J.; Fu, Y.Y.; Li, Y.X.; Chen, L.M.; Chai, K.; Wang, Y.L.
Prostasin inhibits cell invasion in human choriocarcinomal JEG-3 cells (2009), Histochem. Cell Biol., 132, 639-646.

Search for more literature for 3.4.21.B6

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
JEG-3 cell	-	Homo sapiens	-
placenta	prostasin is expressed at a relatively high level in human placental trophoblasts in early pregnant weeks	Homo sapiens	-
trophoblast	prostasin is expressed at a relatively high level in human placental trophoblasts in early pregnant weeks	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	prostasin inhibits cell invasion in human choriocarcinomal JEG-3 cells. Prostasin participates in the proteolytic activation of epithelial sodium channel as well as cleavage of epidermal growth factor receptor extracellular domain in human epithelial cells. Prostasin functions as an invasion suppressor in human trophoblast, participating in the invasion-restrictive regulation of trophoblasts to avoid their over-penetration into the uterine wall	Homo sapiens

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Release 2023.1 (January 2023)