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Literature summary for 3.4.21.B6 extracted from
- Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit (2007), J. Biol. Chem., 282, 6153-6160.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in MDCK cells | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| epithelial sodium channel gamma subunit + H2O | the enzyme activates epithelial sodium channels by inducing cleavage of the gamma-subunit at a site distal to the furin cleavage site | Mus musculus | ? | - |
? |  |
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Release 2023.1 (January 2023)
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