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Literature summary for 3.4.21.B50 extracted from
- A DegU-P and DegQ-dependent regulatory pathway for the K-state in Bacillus subtilis (2016), Front. Microbiol., 7, 1868.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DegQ | - |
Bacillus subtilis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | in domesticated Bacillus subtilis a promoter mutation decreases the rate of degQ transcription. The resulting low level of DegQ decreases DegU phosphorylation, relieving repression at the srfA promoter. As a result more ComS is synthesized and the degradation of ComK by MecA/ClpCP is decreased | Bacillus subtilis |
| physiological function | the regulation of the K-state in undomesticated strains of Bacillus subtilis requires the proper ratio of phosphorylated undunphosphorylated DegU, in accordance with the view that this protein acts as a rheostat for development | Bacillus subtilis |
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