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Literature summary for 3.4.21.B50 extracted from

  • Abfalter, C.; Schubert, M.; Götz, C.; Schmidt, T.; Posselt, G.; Wessler, S.
    HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens (2016), Cell Commun. Signal., 14, 30.
    View publication on PubMed
Search for more literature for 3.4.21.B50

Cloned(Commentary)

Cloned (Comment) Organism
-
 Escherichia coli O127:H6
-
 Proteus mirabilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
E-cadherin + H2O Escherichia coli O127:H6 infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis ?
-
 ?
E-cadherin + H2O Proteus mirabilis infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis ?
-
 ?
E-cadherin + H2O Proteus mirabilis HI4320 infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis ?
-
 ?
E-cadherin + H2O Escherichia coli O127:H6 E2348/69 infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli O127:H6 B7UJW6
-
-
Escherichia coli O127:H6 E2348/69 B7UJW6
-
-
Proteus mirabilis B4EXL6
-
-
Proteus mirabilis HI4320 B4EXL6
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli O127:H6
-
 Proteus mirabilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
E-cadherin + H2O infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis Escherichia coli O127:H6 ?
-
 ?
E-cadherin + H2O infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis Proteus mirabilis ?
-
 ?
E-cadherin + H2O
-
 Escherichia coli O127:H6 ?
-
 ?
E-cadherin + H2O
-
 Proteus mirabilis ?
-
 ?
E-cadherin + H2O infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis Proteus mirabilis HI4320 ?
-
 ?
E-cadherin + H2O
-
 Proteus mirabilis HI4320 ?
-
 ?
E-cadherin + H2O infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis Escherichia coli O127:H6 E2348/69 ?
-
 ?
E-cadherin + H2O
-
 Escherichia coli O127:H6 E2348/69 ?
-
 ?

Synonyms

Synonyms Comment Organism
DegQ
-
 Escherichia coli O127:H6
DegQ
-
 Proteus mirabilis

General Information

General Information Comment Organism
physiological function E-cadherin cleavage is an important step in bacterial pathogenesis Escherichia coli O127:H6
physiological function E-cadherin cleavage is an important step in bacterial pathogenesis Proteus mirabilis