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Literature summary for 3.4.21.B41 extracted from

  • Liu, X.L.; Wazer, D.E.; Watanabe, K.; Band, V.
    Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression (1996), Cancer Res., 56, 3371-3379.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination, in vitro translation Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens activity is down-regulated during oncogenic transformation peptides
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens O43240 gene KLK10 or PRRSL or NES1
-

Source Tissue

Source Tissue Comment Organism Textmining
colon gene expression Homo sapiens
-
heart barely detectable gene expression Homo sapiens
-
lung gene expression Homo sapiens
-
mammary carcinoma cell
-
Homo sapiens
-
mammary epithelium normal strain 76N and oncogenically transforming strain 76R-30 Homo sapiens
-
additional information gene expression is almost lost in breast cancer cell lines Homo sapiens
-
additional information no expression in fibroblasts, peripheral blood leukocytes, brain, placenta, lung, liver, skeletal muscle, and kidney Homo sapiens
-
ovary gene expression Homo sapiens
-
prostate gene expression Homo sapiens
-
small intestine gene expression Homo sapiens
-
testis gene expression Homo sapiens
-
thymus barely detectable gene expression Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polypeptide + H2O
-
Homo sapiens peptides
-
?
polypeptide + H2O activity is down-regulated during oncogenic transformation Homo sapiens peptides
-
?