Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-acetyl-YRFK-chloromethylketone | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-YRFK-4-nitroanilide + H2O | - |
Homo sapiens | N-acetyl-YRFK + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GzmK | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | valosin-containing protein cleavage by granzyme K accelerates an endoplasmic reticulum stress leading to caspase-independent cytotoxicity of target tumor cells | Homo sapiens |