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Literature summary for 3.4.21.B39 extracted from
- Stratum corneum tryptic enzyme in normal epidermis: a missing link in the desquamation process? (2000), J. Invest. Dermatol., 114, 56-63.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloned from RNA isolated from HaCaT cells, expression as His-tagged enzyme in Escherichia coli BL21(DE3) | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9Y337 | gene KLK5 or SCTE | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant as His-tagged enzyme from Escherichia coli BL21(DE3) | Homo sapiens |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| proteolytic cleavage of polypeptides | enzyme is a serine protease | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epidermis | interfollicular epidermis | Homo sapiens | - |
| hair follicle | interfollicular epidermis | Homo sapiens | - |
| hair follicle | terminal | Homo sapiens | - |
| sebaceous follicle | - |
Homo sapiens | - |
| skin | substructure distribution | Homo sapiens | - |
| stratum corneum | plantar | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| polypeptide + H2O | - |
Homo sapiens | peptides | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SCTE | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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