Cloned (Comment) | Organism |
---|---|
cloned from a keratinocyte library, DNA sequence determination and analysis, expression in CHO-K1 cells via infection with Semliki Forest Virus system | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
about, native and recombinant enzyme, gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y337 | can be processed to active enzyme from inactive precursor by trypsin | - |
Homo sapiens | Q9Y337 | gene KLK5 or SCTE | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | N-glycosylated | Homo sapiens |
proteolytic modification | can be processed to active enzyme from inactive precursor by trypsin | Homo sapiens |
Purification (Comment) | Organism |
---|---|
from epidermis | Homo sapiens |
recombinant from CHO-K1 cells | Homo sapiens |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
proteolytic cleavage of polypeptides | enzyme is a serine protease | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
epidermis | - |
Homo sapiens | - |
epithelium | of plantar skin | Homo sapiens | - |
keratinocyte | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
skin | - |
Homo sapiens | - |
stratum corneum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | - |
Homo sapiens | peptides | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 30000-37000, recombinant enzyme, SDS-PAGE | Homo sapiens |
monomer | 1 * 25000-33000, native enzyme, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
strateum-corneum trypsin-like serine protease | - |
Homo sapiens |