Activating Compound | Comment | Organism | Structure |
---|---|---|---|
androgens | slight up-regulation | Homo sapiens | |
estrogen | up-regulaion | Homo sapiens | |
progestins | up-regulaion | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
gene KLK5, genetic organization and structure of the kallikrein gene family, clustered on chromosome 19q13.3-q13.4 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | involved in ovarian cancer | ? | - |
? | |
additional information | Homo sapiens | regulation by steroid homones | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y337 | gene KLK5 or SCTE | - |
Homo sapiens | Q9Y337 | gene KLK5 | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
proteolytic cleavage of polypeptides | substrate binding pocket contains an Asp residue | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | high expression level | Homo sapiens | - |
breast | high expression level | Homo sapiens | - |
ovarian carcinoma cell | gene overexpression in a subset of more aggressive ovarian tumors | Homo sapiens | - |
prostate | - |
Homo sapiens | - |
salivary gland | - |
Homo sapiens | - |
skin | high expression level | Homo sapiens | - |
testis | high expression level | Homo sapiens | - |
thymus | - |
Homo sapiens | - |
thyroid gland | - |
Homo sapiens | - |
trachea | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | involved in ovarian cancer | Homo sapiens | ? | - |
? | |
additional information | regulation by steroid homones | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
K5 | - |
Homo sapiens |
SCTE | - |
Homo sapiens |