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Literature summary for 3.4.21.B30 extracted from
- Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: in vitro degradation and identification of residues required for proteolysis (1998), Genes Dev., 12, 3889-3899.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| K97A | mutant is able to undergo intermolecular cleavage, but not intramolecular self-cleavage | Escherichia coli |
General Stability
| General Stability | Organism |
|---|---|
| highly purified UmuD is specifically degraded in vitro by Lon protease in an ATP-dependent manner, UmuD' is insensitive to proteolysis by Lon | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Escherichia coli | role in SOS mutagenesis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | UmuD is posttranslationally activated by cleavage yielding UmuD' | Escherichia coli |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | role in SOS mutagenesis | Escherichia coli | ? | - |
? | |
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